Review Article

Three-Dimensional Bioprinting Nanotechnologies towards Clinical Application of Stem Cells and Their Secretome in Salivary Gland Regeneration

Table 3

List of secretome components (cytokines, growth factors, and proteinases) from adult stem cells (e.g., bone marrow-derived stem cells and adipose mesenchymal stem cells) that can be potentially used in SG regeneration strategies. More details about each secretome component can be found in [18, 23]. FGF: fibroblast growth factor; FLT3: Fms related tyrosine kinase 3; G-CSF: granulocyte-colony stimulating factor; GM-CSF: granulocyte macrophage-colony stimulating factor; HGF: hepatocyte growth factor; IGF: insulin growth factor; IL: interleukin; MMP: matrix metalloproteinase; OPN: osteopontin; PF4: platelet factor 4; SCF: stem cell factor; SDF1: stromal cell derived factor-1; VEGF: vascular endothelial growth factor.

Secretome componentsReferences

CD26[16]
FGF1[16]
FLT-3[62]
G-CSF[62]
GM-CSF[17]
HGF[16]
IGF-1[17]
IL-1ra[16]
IL-6[17]
IL-16[16]
MMP8[16]
MMP9[16]
OPN[16]
PF4[16]
SCF[62]
SDF1[16]
VEGF[17]