Human Very Small Embryonic-Like Stem Cells Are Present in Normal Peripheral Blood of Young, Middle-Aged, and Aged Subjects

Figure 2

Age-dependent frequency of Lin⁻/CD45⁻ cell subsets expressing (a) CD133, (b) CD34, and (c) CXCR4 into the PB. Three groups of healthy human volunteers were designed according to their age: “young” (20–39 years; ), “middle” (40–59 years; ), and “older” (60–70 years; ). Frequency of Lin⁻ CD45⁻ cell subsets was calculated per mL of PB. Each square represents the number of VSELs/mL per volunteer in each group. The difference between the three groups of volunteers is not statistically significant (; one-way analysis of variance (ANOVA)).

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