Uric Acid-Induced Adipocyte Dysfunction Is Attenuated by HO-1 Upregulation: Potential Role of Antioxidant Therapy to Target Obesity

Figure 6

(a) NADPH oxidase expression by western blot analysis. Data are shown as mean band density normalized to β-actin. Results are means ± SE, /group. versus CTR; versus UA; and versus UA + CoPP. (b) Measurement of superoxide levels in pelleted cells at day 14 of adipogenesis in human MSCs treated with 5 mg/dL uric acid with or without CoPP, in the presence or absence of SnMP. Values represent means ± SEM of five independent treatments. versus CTR; versus UA; and versus UA + CoPP.

(a)

(b)