The Role of miRNAs in the Regulation of Pancreatic Cancer Stem Cells

Table 1

Self-renewal pathways in PCSCs.

Signaling pathways	Effects on tumorigenesis and drug resistance	Targets	Reference
Hedgehog	Proliferation	ALDH^+ CD44^+CD24^+ESA^+	[32–34]
ALK4	Invasion and metastasis	CD133^+	[35]
Notch	Proliferation	ALDH^+	[34]
c-Met	Drug resistance	c-Met^+, CD133^+	[36]