Growth Hormone-Releasing Hormone and Its Analogues: Significance for MSCs-Mediated Angiogenesis

Figure 3

Effects of GHRH agonists on MSCs. Multiple cell types including MSCs express the GHRH receptor and can respond to GHRH agonists and antagonists. Receptor activation communicates with diverse survival pathways that transmit paracrine and autocrine signals to promote cytoprotection, antiapoptosis, and angiogenesis.