Skeletal Muscle-Derived Stem/Progenitor Cells: A Potential Strategy for the Treatment of Acute Kidney Injury

Figure 5

MDSPCs impact on functional recovery of damaged kidney. Gentamicin-induced acute kidney injury was validated by the presence of physiological and functional changes in all rats from GM and GM + MDSPCs groups ((a), (b), (c), and (d), D8). There was no significant difference in urine volume between GM and GM + MDSPCs groups at any time point ((a); ). The MDSPCs accelerated the recovery after AKI, as reflected by significantly higher GFR ((b); ), increased urinary creatinine levels ((c); ), and lower serum creatinine ((d); ) as compared to the GM group rats that were not treated with MDSPCs. , significant difference.

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(b)

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