Research Article
Effects of Extracellular Vesicles Derived from Human Umbilical Cord Blood Mesenchymal Stem Cells on Cell Immunity in Nonobese Mice
Figure 5
Effects of HucMSC-EVs on inflammatory cytokine and transcription factor T-bet/GATA-3. (a) HucMSC-EVs affected the level of serum inflammatory cytokines in NOD mice after intravenous injection for 8 weeks; (b) HucMSC-EVs affected the mRNA expression of spleen transcription factor T-bet/GATA-3 and inflammatory cytokines IL-2, IFN-γ, IL-4, and IL-10. (c(c1 and c2)) HucMSC-EVs affected the protein expression of spleen transcription factor T-bet/GATA-3 and inflammatory cytokines IL-2, IFN-γ, IL-4, and IL-10. , , compared with control group.
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