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Adult Stem Cells in Translational Research

Call for Papers

The first bone marrow transplantation had passed its 50th year anniversary, and with that in mind, it is only within the last decade that stem cell investigation has taken flight. Research within this more recent movement in the stem cell field started with the explosion of possibilities tied to embryonic stem cells or what we call pluripotent stem cells due to their limitless abilities to crossover all three germ layers and become any type of cell within the human biosystem.

Further investigations led to the possible use of adult stem cells, which are already partially committed as a source as these cells do not require guidance for differentiation and are already past the tumor formation stage giving them an advantage over embryonic stem cells. However, adult stem cells have a limited ability in regard to which cell types they can become, moving us forward into the induced pluripotent stem (iPS) cell research, which allows somatic cells to overcome their disadvantage in transdifferentiation. The capabilities of adult stem cells and their copartner iPS cells, such as autologous and sometimes homologous use, will allow for an easier transition into the clinical phase aspect of stem cell progression as suggested by many clinical trials that are currently in progress using mesenchymal stem cells as the transplantation cell of choice.

We invite investigators to contribute their original research articles as well as review articles that provide novel insights on how to bring stem cell therapies into the clinical phase by increasing safety and efficacy. Potential topics include, but are not limited to:

  • Characterization of adult stem cells available for potential clinical use
  • Cell delivery method
  • Control of stem cell differentiation
  • Control of stem cell migration
  • Quality control of transplantable materials
  • Materials and nanoscience to improve efficacy of stem cell therapy
  • Factors to control stem cell biology
  • Characterization of cell fate following transplantation
  • Elucidation of therapeutic mechanisms
  • Consideration of side effects

Before submission authors should carefully read over the journal’s Author Guidelines, which are located at http://www.hindawi.com/journals/sci/guidelines/. Prospective authors should submit an electronic copy of their complete manuscript through the journal Manuscript Tracking System at http://mts.hindawi.com/submit/journals/sci/astr/ according to the following timetable:

Manuscript DueFriday, 29 November 2013
First Round of ReviewsFriday, 21 February 2014
Publication DateFriday, 18 April 2014

Lead Guest Editor

  • Kiminobu Sugaya, Burnett School of Biomedical Sciences, College of Medicine, University of Central Florida, Orland, FL, USA

Guest Editors

  • Rubén Berrocal, National Secretary of Science, Technology and Innovation, Panama City, Panama
  • Amit Patel, University of Utah, Salt Lake City, UT, USA