Scientifica

Review Article

Plasma Membrane Transporters in Modern Liver Pharmacology

Table 1

Identified potential substrates of hepatic forms of OATPs with pharmacological interest.
 OATP1B1OATP1B3OATP1A2
Substrates Benzylpenicillin  
Bile acid derivatives (BAMETS)Bile acid derivatives (BAMETS)Bile acid derivatives (BAMETS)
Bilirubin and its conjugatesBilirubin conjugates 
BosentanBosentan 
BQ-123BQ-123BQ-123
BromosulfophthaleinBromosulfophthaleinBromosulfophthalein
Caspofungin  
CerivastatinCholecystokinin-8 
Cholic acid Cholic acid
DHEA sulphateDHEA sulphateDHEA sulphate
 Deltorphin IIDeltophorin II
 Digoxin 
DPDPEDPDPEDPDPE
 Docetaxel 
EnalaprilEnalapril 
Estradiol 17β-glucuronideEstradiol 17β-glucuronide 
Estrone-3-sulphate Estrone-3-sulphate
 FexofenadineFexofenadine
FlavopiridolFlavopiridol 
FluvastatinFluvastatin 
GlycocholateGlycocholateGlycocholate
Irinotecan and SN-38Irinotecan and SN-38 
  Imatinib
  Levofloxacin
Leukotriene C4Leukotriene C4 
MethotrexateMethotrexateMethotrexate
Microcystin-LRMicrocystin-LRMicrocystin-LR
OlmesartanOlmesartan 
 OuabainOuabain
PaclitaxelPaclitaxel 
PhalloidinPhalloidin 
  D-Penicillamine
Pravastatin Pravastatin
Prostaglandin E2 Prostaglandin E2
RifampicinRifampicin 
RosuvastatinRosuvastatinRosuvastatin
  Saquinavir
TaurocholateTaurocholateTaurocholate
 Telmisartan 
Thromboxane B2  
ThyroxineThyroxineThyroxine
TriiodothyronineTriiodothyronineTriiodothyronine
Troglitazone sulphate  
ValsartanValsartan