Plasma Membrane Transporters in Modern Liver Pharmacology

Table 2

Identified potential substrates of hepatic forms of OATs, OCTs, and OCTNs with pharmacological interest.

	OAT2	OCT1	OCTN1
Substrates	p-Aminohippurate	Acetylcholine	L-Carnitine
	Acetylsalicylate	Acyclovir	Ergothioneine
	Allopurinol	Cimetidine	Pyrilamine
	Bumetanide	Choline	Quinidine
	Cyclic AMP	Dopamine	Quinine
	DHEA sulphate	Epinephrine	Tetraethylammonium
	Estrone-3-sulphate	Famotidine	Verapamil
	5-Fluorouracil	Ganciclovir
	Glutarate	Histamine
	α-Ketoglutarate	Imatinib
	Methotrexate	Lamivudine
	Ochratoxin A	Metformin
	Paclitaxel	N-Methylnicotinamide
	Prostaglandin E2	1-Methyl-4-phenylpyridinium
	Prostaglandin F2α	Norepinephrine
	Raloxifene	Quinine
	Salicylate	Ranitidine
	Tetracycline	Serotonin
	Valproic acid	Spermidine
	Zidovudine	Spermine
		Tetraethylammonium
		Zalcitabine