Effect of the APOE Polymorphism and Age Trajectories of Physiological Variables on Mortality: Application of Genetic Stochastic Process Model of Aging

Figure 1

Average age trajectories (±S.E.) of total cholesterol (“CH”) and diastolic blood pressure (“DBP”) for long-lived female (life span (“LS”) ≥ 90 years) and male (LS ≥ 85 years) carriers (“e4”) and noncarriers (“No e4”) of the APOE e4 allele in the Framingham Heart Study (original cohort). “N” denotes the number of individuals.

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