Review Article

The Neuropathology of Autism

Figure 7

A 50 μm vibratome cut section demonstrates vertical minicolumnar organization in the human inferior frontal cortex via immunohistochemistry section incubated with primary antibodies to microtubule-associated protein type 2 (MAP2) that labels apical dendrites (Figure 1; 1000x; red circle). Note the radial organization of columnar components in this tangential section through layer IV. This represents the center of a cortical minicolumn.
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