The Insulin-Like Growth Factor System and Nutritional Assessment

Table 3

Effect of malnutrition and obesity on serum levels of proteins of the IGF axis.

Protein	Malnutrition	References	Obesity	References
IGF-I	↓	[36, 37]	U/↑/↓	[38–45]
IGF-II	↓	[34, 46, 47]	↑	[48, 49]
Free IGF-I	↓	[50, 51]	U/↑/↓	[43–45, 48, 49, 52]
Free IGF-II	↓	[49]	↑	[49]
IGFBP-1	↑	[51]	↓	[53, 54]
IGFBP-2	↑	[34]	↓	[55, 56]
IGFBP-3	↓	[57–59]	↑	[60]

Key: ↑ increase; ↓ decrease; U unchanged.