SKIP Downregulation Increases TGF-<i>β</i>1-Induced Matrix Metalloproteinase-9 Production in Transformed Keratinocytes

<table>SKIP depletion enhances TGF-<i>β</i>1-induced MMP-9 promoter transactivation. Transactivation of MMP-9 promoter in PDV/M and AS-S cells transfected with empty vector (EV) or plasmid containing HA-SKIP. MMP-9 promoter activity was assayed in cells stimulated and not with TGF-<i>β</i>1 for 48 h by using luciferase inducible activity. <i>β</i>-Gal was used as internal control of transfection. Insert, western blot showing the correct expression of ectopic SKIP. Alpha Tubulin (<i>α</i>-Tub) was used a loading control protein.</table>

Scientifica

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Figure 3

Figure 3: SKIP Downregulation Increases TGF-<i>β</i>1-Induced Matrix Metalloproteinase-9 Production in Transformed Keratinocytes 

Scientifica

SKIP Downregulation Increases TGF-β1-Induced Matrix Metalloproteinase-9 Production in Transformed Keratinocytes

Figure 3