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Figure 3: The extracellular domain of TF on a modeled lipid membrane. The figure shows in red the three sites of glycosylation ( , and ). Highlighted in green are residues important for TF interaction with factor VIIa ( , , , , , , , , , , , , , , , , and ). Highlighted in magenta are residues important for the interaction with factor X ( and ). Highlighted in aqua are the residues important for TF interaction with the membrane ( , , , , , , and ). Also shown in yellow are the two disulfide bridges of TF at positions - and - . (This figure was originally published in Biochim Biophys Acta) [10].