Table 1: Clinical and laboratory characteristics of bullous skin diseases.

DiseaseSkinMucosaNikolsky sign*DIF**IIFAutoantigen

Bullous pemphigoid+IIBMZBMZBP180
Pemphigus vulgaris+/−+ICWPCWPDsg3 +/− Dsg1
Pemphigus foliaceus+ICWPCWPDsg1

Nikolsky sign I is the classical Nikolsky sign; the alternative Nikolsky sign II was originally described as the Asboe-Hansen sign.
**BMZ: basement membrane zone; BP: bullous pemphigoid; CWP: chicken-wire pattern; DIF: direct immunofluorescence; Dsg: desmoglein; IIF: indirect immunofluorescence.