Table 3: Diagnostic accuracy of the main laboratory markers for IA.

ReferenceMethodSampleSensitivityaSpecificityaDORb

Mengoli et al. 2009 [183]PCR (1)Blood0.88 (0.75–0.94)0.75 (0.63–0.84)22.11 (7.77–62.92)
Mengoli et al. 2009 [183]PCR (2)Blood0.75 (0.54–0.88)0.87 (0.79–0.93)21.33 (6.86–46.63)
Leeflang et al. 2008 [180]GMBlood0.79 (0.61–0.93)0.82 (0.71–0.83)17.10c
Sun et al. 2010 [182]GMBlood0.66 (0.61–0.70)0.9 (0.89–0.90)19.1 (12.67–28.79)
Guo et al. 2010 [184]GMBAL0.86 (0.70–0.94)0.89 (0.85–0.92)51.0c
Onishi et al. 2012 [185]BDGBlood0.77 (0.71–0.82)0.83 (0.82–0.84)23.2 (9.9–54.4)

Sensitivity and specificity as proportions with 95% confidence intervals (CI) given in brackets, bDOR diagnostic odds ratio, ccalculated from sensitivity and specificity data in the references, 95% CI not calculable.