Immune Response in Thyroid Cancer: Widening the Boundaries

Figure 2

COX-2 is a catalyzing enzyme that converts cellular arachidonic acid to prostaglandin, contributing to trigger inflammation. Many reports have demonstrated that COX-2 is not only responsible for cell proliferation and transformation but also responsible for inducing angiogenesis. In addition, migration and invasiveness have been associated to overexpression of COX-2.