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Figure 4: Migraine status in 150 consecutive patients with Amplatzer PFO closure at an average of 5 ± 2 years of follow-up. The average age of the patients was 51 ± 11 years, 61% were males, and 91% had complete closure by 6-month transesophageal echocardiography. Antiplatelet treatment had been stopped at the latest 6 months after the intervention.