Computational Insights into Substrate and Site Specificities, Catalytic Mechanism, and Protonation States of the Catalytic Asp Dyad of <b><i>β</i></b>-Secretase

<table>General acid-base mechanism utilized for peptide hydrolysis.</table>

Scientifica

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Figure 3

Figure 3: Computational Insights into Substrate and Site Specificities, Catalytic Mechanism, and Protonation States of the Catalytic Asp Dyad of <b><i>β</i></b>-Secretase 

Figure 3 | Computational Insights into Substrate and Site Specificities, Catalytic Mechanism, and Protonation States of the Catalytic Asp Dyad of β-Secretase 