757549.fig.005a
(a)
757549.fig.005b
(b)
Figure 5: Bipartite peptide-nucleic acids (PNAs) and tripartite MTX-PNA. (a) General structure of PNA. (b) Designed bipartite PNA targeting the tau RNA stem-loop structure. Antisense PNA regions in purple; ethylene glycol linker (egl) in green; lysines added for solubility and cell penetration in blue.