Review Article

Influenza Viral Manipulation of Sphingolipid Metabolism and Signaling to Modulate Host Defense System

Figure 5

Interaction between SK1 and viruses. (a) SK1 inhibits BVDV replication, whereas SK1 heightens cellular susceptibility to the infection with influenza virus or HCMV. (b) BVDV and DENV decrease SK1 expression/activation, whereas influenza virus, HCMV, and RSV increase SK1 level/activation.
793815.fig.005a
(a)
793815.fig.005b
(b)