Biological Evaluation of Pupalia lappacea for Antidiabetic, Antiadipogenic, and Hypolipidemic Activity Both In Vitro and In Vivo

Table 5

Effect of Pupalia lappacea in body weight of STZ induced diabetes in rats.

S. number	Treatment group	Dose (mg/kg)	Body weight (g/kg)
			Day 0	Day 7	Day 14	Day 21	Day 28
1	NC	Untreated	185 ± 1.3	190 ± 1.5	196 ± 2.4	201 ± 2.1	209 ± 1.3
2	DC	Vehicle	188 ± 2.5	182 ± 2.7	164 ± 2.8	123 ± 3.1	107 ± 2.5
4	RF	5.0	188 ± 1.2	179 ± 2.3	172 ± 2.6	176 ± 2.3	186 ± 2.1
5	AS001	250	186 ± 3.1	185 ± 3.1	168 ± 3.3	167 ± 2.7	168 ± 3.6
6	AS002	500	187 ± 6.1	174 ± 2.9	169 ± 3.2	175 ± 1.9	183 ± 2.6

NC = normoglycemic control, DC = diabetic control, and RF = reference group (glibenclamide, 5.0 mg/kg). Values are expressed as mean ± SEM (number of animals, ), significantly different at , when compared with diabetic control group.