Research Article

Analysis and Enhancements of a Prolific Macroscopic Model of Epilepsy

Table 1

Model parameters from Wendling et al. [18].

Param.InterpretationValue

Average excitatory synaptic gain5 mV
Average slow inhibitory synaptic gainSee Figure 2
Average fast inhibitory synaptic gainSee Figure 2
Dendritic average time constant in the feedback excitatory loop100 s−1
Dendritic average time constant in the slow feedback inhibitory loop50 s−1
Somatic average time constant in the fast feedback inhibitory loop350 s−1
, Mean number of synaptic contacts in the excitatory feedback loop135,
, Mean number of synaptic contacts in the slow feedback inhibitory loop
, Mean number of synaptic contacts in the fast feedback inhibitory loop,
Mean number of synaptic contacts between slow and fast inhibitory interneurons