Research Article
Development and Characterization of Novel Floating-Mucoadhesive Tablets Bearing Venlafaxine Hydrochloride
Table 7
Swelling behavior of matrix tablets.
| | Formulation code | Initial weight (mg) | Initial thickness (mm) | Initial diameter (mm) | Final weight (mg) | Final thickness (mm) | Final diameter (mm) | Swelling index |
| | FC1 | 234.11 ± 3.05 | 3.97 ± 0.01 | 8.98 ± 0.01 | 552.59 ± 3.11 | 4.42 ± 1.08 | 18.16 ± 0.38 | 136.03 | | FC2 | 240.20 ± 4.35 | 3.98 ± 0.02 | 8.97 ± 0.02 | 578.52 ± 1.32 | 4.50 ± 0.74 | 18.52 ± 1.20 | 140.84 | | FC3 | 244.18 ± 1.69 | 3.97 ± 0.01 | 8.99 ± 0.01 | 607.10 ± 5.06 | 4.56 ± 0.89 | 18.73 ± 1.48 | 148.67 | | FC4 | 250.10 ± 1.71 | 3.99 ± 0.02 | 8.97 ± 0.01 | 637.22 ± 3.40 | 4.61 ± 1.21 | 18.85 ± 0.92 | 154.78 | | FC5 | 239.58 ± 1.01 | 3.98 ± 0.01 | 8.98 ± 0.02 | 578.48 ± 2.25 | 4.53 ± 1.42 | 18.62 ± 1.34 | 141.45 | | FC6 | 250.09 ± 1.89 | 3.96 ± 0.01 | 8.99 ± 0.02 | 648.86 ± 4.13 | 4.63 ± 1.27 | 18.89 ± 0.88 | 159.45 | | FC7 | 255.58 ± 3.29 | 3.97 ± 0.02 | 8.97 ± 0.01 | 681.68 ± 2.67 | 4.66 ± 0.54 | 18.93 ± 1.53 | 166.72 | | FC8 | 250.17 ± 1.23 | 3.99 ± 0.02 | 8.99 ± 0.01 | 654.25 ± 3.28 | 4.62 ± 0.28 | 18.99 ± 0.67 | 161.52 | | FC9 | 254.21 ± 3.53 | 3.98 ± 0.01 | 8.98 ± 0.01 | 678.17 ± 1.44 | 4.64 ± 0.78 | 19.14 ± 0.25 | 166.78 | | FC10 | 259.67 ± 4.42 | 3.99 ± 0.02 | 8.97 ± 0.02 | 703.67 ± 2.87 | 4.68 ± 0.38 | 19.27 ± 1.44 | 170.99 |
|
|
Mean ± SD; ; FC: formulation code.
|
