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Scientifica
/
2016
/
Article
/
Tab 6
/
Research Article
In Vitro
and
In Vivo
Evaluation of Niosomal Formulation for Controlled Delivery of Clarithromycin
Table 6
Pharmacokinetic parameter of drug determined after administered of plain drug and niosomal formulation.
Sr. number
Parameters
Free drug
NC
2
1
2.488
g/mL
4.321
g/mL
2
6 hr
4 hr
3
AUC
24.50
g/mL⋅hr
35.50
g/mL⋅hr
4
AUMC
160
g/mL⋅hr
2
670
g/mL⋅hr
2
5
MRT
6.66 hr
18.87 hr