Asthma Control and Its Relationship with Obstructive Sleep Apnea (OSA) in Older Adults
Table 1
Demographic and physiologic characteristics, medical history, and medication use for older and younger asthma subjects.
Characteristic
Mean ± SD, or Number (%) of Subjects
P value
Older ()
Younger ()
Age (y)
<0.0001
Gender (female)
95 (62%)
448 (68%)
0.14
BMI ()
0.36
<25
38 (25%)
214 (32%)
0.17
25–29.9
52 (34%)
204 (31%)
≥30
64 (42%)
241 (37%)
Race
0.65
African-American
7 (5%)
35 (5%)
White
145 (94%)
598 (91%)
Others*
2 (1%)
26 (4%)
Current smokers
4 (3%)
33 (5%)
0.28
Age of asthma onset (y)
<0.0001
Age at physician-established asthma diagnosis (y)
<0.0001
% predicted
0.0002
FVC% predicted
<0.0001
/FVC
<0.0001
% predicted
<0.0001
History of rhinitis
137 (89%)
598 (91%)
0.50
History of chronic sinusitis
54 (35%)
192 (29%)
0.15
History of nasal polyps
32 (21%)
88 (13%)
0.02
History of GERD
84 (55%)
285 (43%)
0.01
History of psychiatric disease
29 (19%)
190 (29%)
0.01
Using inhaled corticosteroid (ICS)
132 (86%)
500 (76%)
0.008
Using oral corticosteroid
16 (10%)
54 (8%)
0.38
Using inhaled long-acting bronchodilator
97 (63%)
379 (58%)
0.22
Using antileukotriene agents
32 (21%)
182 (28%)
0.08
Using inhaled anticholinergic
10 (6%)
49 (7%)
0.69
Using theophylline
4 (3%)
13 (2%)
0.54
Definition of abbreviations: SD: standard deviation; BMI: body mass index; %: forced expiratory volume in first second; FVC%: forced vital capacity; %: forced expiratory flow between 25% and 75% of vital capacity (all of these physiologic variables are expressed as percentages of predicted values); GERD: gastroesophageal reflux disease.
*Included Asians, Hawaiian/Pacific Islander, and American Indians/Alaskans.
