Screening for Sleep Apnoea in Mild Cognitive Impairment: The Utility of the Multivariable Apnoea Prediction Index

Table 1

A comparison of clinical, self-report, and polysomnographic data between MCI and control subjects.

	Control; Mean ± SD	MCI; Mean ± SD	𝑡 value (df)/𝑧	𝑃 value
Clinical
Age (years)	63.5±8.7	65.5±9.0	−0.98 (71)	0.333
Body mass index	27.1±4.0	27.6±5.5	−0.43 (72)	0.669
Weight (kg)	75.9±14	78.0±16	−0.60 (72)	0.552
Height (cm)	167±10	168±11	−0.43 (72)	0.668
CIRS, total score	3.0±2.3	5.9±6.4	−2.57 (67)	𝟎.𝟎𝟏𝟐^∗
MMSE score	29.2±1.1	28.1±1.5	3.75 (72)	<𝟎.𝟎𝟎𝟏^∗∗
Self-report
MAPI	0.3±0.2	0.4±0.2	−1.30 (72)	0.199
PSQI, global score	5.4±4.0	7.0±3.4	−1.83 (69)	0.072
PSQI, sleep efficiency (%)	77.6±10	75.5±14	0.63 (68)	0.533
Overnight polysomnography
Apnoea-hypopnoea index	11.9±10	16.4±16	−1.20 (47)	0.236
Total sleep time (minutes)	377±73	385±100	−0.41 (72)	0.682
Sleep efficiency (%)	77.6±10	75.6±14	0.73 (72)	0.468
WASO (mins)	96.9±53	97.9±56	−0.08 (72)	0.938
Lowest oxygen desaturation (%)	87.6±5.0	87.9±8.4	−0.19 (72)	0.854
Average oxygen desaturation (%)	4.1±1.4	6.5±13	−1.10 (72)	0.273
Oxygen desaturation index	23.9±21.6	39.3±65.4	−1.21	0.228
Non-REM sleep AHI	9.5±9.9	14.2±15	−1.31 (47)	0.198
REM sleep AHI	18.6±15	19.8±16	−0.11 (47)	0.916

^∗𝑃<0.05, **𝑃<0.01.
MCI: mild cognitive impairment; CIRS: cumulative illness rating scale; MMSE: mini-mental state examination; MAPI: multivariable aponea prediction index; PSQI: pittsburgh sleep quality index; AHI: apnoea-hypopnoea index; WASO: wake after sleep onset; REM: rapid eye movement.