]>

Table 1: Data for the Group 3 patients, in whom there was no clearly defined association between malignancies.

Patient Age (at diagnosis of second tumour)yrs Sex Second tumour (primary bone sarcoma) Initial malignancy (Ca: carcinoma) Site of second tumour Lag (time to second tumour)yrs 1 72 F Chondrosarcoma Ca breast Prox femur 14 2 59 F Chondrosarcoma Ca breast Prox humerus 1 3 50 F Chondrosarcoma Ca breast Prox femur 16 4 58 F Chondrosarcoma Ca breast Prox humerus 2 5 60 F Chondrosarcoma Ca breast Distal femur 0 6 60 F Chondrosarcoma Ca bronchus Prox tibia 2 7 72 F Chondrosarcoma Ca colon Distal femur 4 8 44 M Chondrosarcoma Ca oesophagus Pelvis 6 9 58 M Chondrosarcoma Ca rectum Prox tibia 7 10 82 M Chondrosarcoma Leukaemia Prox femur 6 11 52 F Chondrosarcoma Malignant melanoma Pelvis 3 12 66 F Chondrosarcoma Ca breast Metatarsal 0 13 66 F Chordoma Ca breast Sacrum 0 14 55 F Chordoma Ca breast Sacrum 12 15 29 F Ewings sarcoma Ca kidney Prox femur 0 16 12 F Ewings sarcoma Hodgkin’s lymphoma Fibula 6 17 9 M Ewings sarcoma Leukaemia Prox tibia 5 18 78 M Fibrosarcoma Malignant fibrous histiocytoma (soft tisssue) Pelvis 2 19 41 F Fibrosarcoma Malignant melanoma Prox femur 3 20 84 F Leiomyosarcoma Ca breast Distal fibula 8 21 47 F Malignant fibrous histiocytoma Hodgkin’s lymphoma Distal femur 6 22 39 M Malignant fibrous histiocytoma Seminoma Distal femur 10 23 27 F Malignant fibrous histiocytoma Ca breast Prox femur 2 24 66 M Osteosarcoma Ca bladder Scapula 3 25 63 F Osteosarcoma Ca breast Prox femur 5 26 10 M Osteosarcoma Hodgkin’s lymphoma Prox humerus 3 27 33 F Osteosarcoma Malignant melanoma Prox tibia 4 28 8 F Osteosarcoma Rhabdomyosarcoma Prox tibia 5 29 12 M Osteosarcoma Rhabdomyosarcoma Prox femur 11 30 81 F Sarcoma Ca breast Prox fibula 0 31 72 F Sarcoma Ca breast Scapula 3 32 69 M Spindle cell sarcoma Ca prostate Scapula 1 33 81 F Spindle cell sarcoma Ca colon Prox tibia 18