Factor VII Activating Protease Polymorphism (G534E) Is Associated with Increased Risk for Stroke and Mortality

<table>Marburg II hazard ratios for vascular endpoints in GENDER and PROSPER. As the Marburg II polymorphism does not lead to altered enzymatic activity, the similar trends that were observed for this variant are probably a result of the high linkage disequilibrium between the Marburg variants. Despite high confidence intervals, a significant effect was observed on mortality.</table>

Stroke Research and Treatment

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Figure 2

Figure 2: Factor VII Activating Protease Polymorphism (G534E) Is Associated with Increased Risk for Stroke and Mortality 