Lentiviral-Mediated shRNA Silencing of PDE4D Gene Inhibits Platelet-Derived Growth Factor-Induced Proliferation and Migration of Rat Aortic Smooth Muscle Cells
Figure 2
PDE4D regulates PDGF-induced VSMC proliferation. VSMC viability was determined using MTT assay at 48 hours postinfection. Data are mean ± SEM of 3 separate experiments performed in triplicate. *P less than .05 versus control. #P less than .05 versus nonsense shRNA.