Ischemic Stroke during Pregnancy and Puerperium

Table 2

Studies of pregnancy-related stroke since 1985.

Author, year	Methodology	Study period	Postpartum period	Deliveries N°	Total stroke N°	Ischemic stroke N°	Ischemic stroke incidence (per deliveries)	Mortality N° (%)	Ischemic stroke mortality	Notes
Wiebers and Whisnant, 1985	Retrospective population-based study	1955–1979	NR	26099^∗	1	1	NR	NR	NR	*Live births
Simolke et al., 1991	Retrospective single hospital-based study	1984–1990	NR	89913	15	7	1 in 10000'	2 (13,3)	1 (14,3)	*Including also cerebral venous thrombosis
Awada et al., 1995	Retrospective hospital-based study	1983–1993	15 days	NR	12	9	NR	4 (33)	1 (11,1)
Sharshar et al., 1995	Retrospective and prospective multihospital-based study	1989–1992	2 weeks	348295	31	15	4,3 per 100 000	4 (13)	0
Kittner et al., 1996	Retrospective population-based study	1988–1991	6 weeks	141243	31	17*	11 per 100 000	NR	NR	*Including cerebral venous thrombosis (1 patient)
Witlin et al., 1997	Retrospective single hospital-based study	1985–1995	4 weeks	79301	24	5	NR	7 (29,2)	NR
Jiagobin and Silver, 2000	Retrospective single hospital-based study	1980–1997	6 weeks	50711	34	21*	41 per 100 000	3 (9)	0	*Including cerebral venous thrombosis (8 patients);
Skidmore et al., 2001	Retrospective hospital-based study	1992–1999	12 weeks	58429	36	21	NR	1 (2,7)	1 (4,7)
Ros et al., 2001	Retrospective, records from birth register, Sweden	1987–1995	6 weeks	1003489	NR	NR	4 per 100 000	NR	NR
Jeng et al., 2004	Retrospective single hospital-based study	1984–2002	6 weeks	49796	49	16	32,1 per 100 000	10 (20)	2 (13)
Liang et al., 2006	Retrospective single hospital-based study	1992–2004	6 weeks	66781	26	11*	16,5 per 100000	5 (19)	1 (9,1)	*Including cerebral venous thrombosis (3 patients)

NR: not reported