A Comparison of Cooling Techniques to Treat Cardiac Arrest Patients with Hypothermia
Table 1
Baseline characteristics and adverse events during the first week in the endovascular-() and surface-cooled groups ().
Characteristic/adverse event
Endovascular number (%)
Surface number (%)
P valuea
Baseline characteristic
Mean age (years)
.28
Sex (males)
18 (69%)
12 (80%)
.22
Mean weight (kg)
.15
Duration of the arrest (min)
31
24
.13
Ventricular fibrillation arrests
12 (46%)
1 (7%)
.008
Median time from arrest to initiation of cooling protocol (min)
277
481
.16
Median Bladder T at initiation of cooling (°C)
36.4
36.4
.76
Renal failure on admissionb
10 (38%)
10 (67%)
.06
Adverse Events
Hypotensionc
10 (38%)
4 (27%)
.21
Bradycardiad
18 (69%)
8 (53%)
.16
Other arrhythmias
6 (23%)
4 (27%)
.28
New infection in 1st week
16 (62%)
8 (53%)
.23
Pneumonia
14 (54%)
7 (47%)
.23
Sepsis
1 (4%)
0 (0%)
.63
Pancreatitis
0 (0%)
0 (0%)
—
Renal failure 1st weeke
6 (23%)
4 (27%)
.25
Hemodialysis
1 (4%)
1 (7%)f
.48
Coagulopathyg
6 (23%)
4 (27%)
.77
Groin hematoma
0 (0%)
N/A
—
Skin injury
0 (0%)
0 (0%)
—
Transfusion pRBC
6 (23%)
4 (27%)
.28
Transfusion of platelets
1 (4%)
0 (0%)
.63
Seizuresh
2 (8%)
2 (13%)
.33
Deep venous thrombosisi
3 (12%)
1 (7%)
.38
Pulmonary embolism
1 (4%)
0 (0%)
.63
a values calculated from Fisher’s exact test and Wilcoxon rank-sum test; bcreatinine ≥1.5 mg/dL; cmean arterial pressure <70 mm Hg and requiring pressors; dheart rate <60/min; erise in creatinine ≥0.5 mg/dL; falready on hemodialysis as outpatient; gINR >1.5 or PTT > 40 sec within 48 hours of cooling; hnot including clinical evidence of status myoclonus.