712903.fig.003a
(a)
712903.fig.003b
(b)
712903.fig.003c
(c)
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(d)
712903.fig.003e
(e)
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(f)
Figure 3: Cutaneous and ophthalmological symptoms of PXE. Plaques of papules in the neck region (a), increased skin laxity (b) and mucosal involvement with yeloowish pattern on the inner lip (c). The retinopathy consists of peau d’orange (d, oval), angioid streaks (d, arrowed), retinal hemorrhaging (e). In some cases calcifications of Bruch’s membrane can be seen as comets or comet tails (f, arrowed).