Infection after Acute Ischemic Stroke: Risk Factors, Biomarkers, and Outcome
Table 2
Univariate associations of laboratory markers of infection with the development of an infection and serious infection during the hospital stay.
No infection
Infection
Serious infection
*
Normal Range
Markers of Infection
Mean temperature day 1 (°C)
<.0001
.001
Mean temperature day 3 (°C)
<.0001
<.0001
Procalcitonin day 1 (ng/mL)
NS
NS
<0.5
Procalcitonin day 3 (ng/mL)
NS
.04
<0.5
Procalcitonin day 5 (ng/mL)
.002
<.0001
<0.5
Interleukin-6 day 1 (pg/mL)
.019
.009
<6.0
Interleukin-6 day 3 (pg/mL)
<.0001
<.0001
<6.0
Interleukin-6 day 5 (pg/mL)
.004
<.0001
<6.0
Lipopolysaccaride-binding protein day 1 (mcg/mL)
.014
.008
<8.4
Lipopolysaccaride-binding protein day 3 (mcg/mL)
.001
<.0001
<8.4
Lipopolysaccaride-binding protein day 5 (mcg/mL)
<.0001
<.0001
<8.4
C-reactive protein day 1 (mg/L)
NS
.022
0–5.0
C-reactive protein day 3 (mg/L)
<.0001
<.0001
0–5.0
C-reactive protein day 5 (mg/L)
<.0001
<.0001
0–5.0
White blood cells day 1 (Gpt/L)
.006
<.0001
4.0–11.0
White blood cells day 3 (Gpt/L)
.034
.034
4.0–11.0
White blood cells day 5 (Gpt/L)
.01
.006
4.0–11.0
Monozyte HLA-DR expression day 1 (%)
.039
.034
>30
Monozyte HLA-DR expression day 3 (%)
.002
.011
>30
Monozyte HLA-DR expression day 5 (%)
.014
.004
>30
Data are shown as number for dichotomized variables mean ± standard error of the mean (SEM) for normally distributed continuous variables, or median (range) for abnormally distributed continuous variables. * value for analysis of serious infection versus no infection.
