Table 1: Baseline characteristics and aetiology.

<85 years oldOldest OldGroup comparison
value

n (%)1399 (93)106 (7)
Age, y-o (median, range)71 (18–84)88 (85–101)
Gender
 Female, (%)630 (45.1)73 (69.9)< 0.001
Risk factors
 Arterial hypertension, (%)837 (60.4)81 (78.6)<0.001
 Diabetes mellitus, (%)280 (20.2)14 (13.6)0.103
 Dyslipemia, (%)485 (35.2)29 (28.2)0.149
 Current smoking, (%)322 (23.3) 1 (1)< 0.001
 Atrial fibrillation, (%)241 (17.4)31 (30.1)0.001
Prior antiplatelet therapy, (%)280 (20.2)34 (33)0.002
Prior anticoagulation therapy, (%)57 (4.1)7 (6.8)0.149
Elevated BP (>185/110 mg Hg) on admission n (%)200 (14.8)27 (26.7)0.001
Blood glucose on admission (mmol/dL), median (IQR)119 (102–144)118 (10.5–151.5)0.415
Baseline NIHSS, median (IQR)13 (8–18)16 (10–21)< 0.001
Time (min), median (IQR)
 Stroke onset-to-door time75 (55–110)85 (64–115)0.049
 Door-to-treatment time58 (42–76)58 (45–74)0.808
 Stroke onset-to-treatment time144.5 (115–173.7)142.5 (120–186.2)0.265
Aetiology, (%)
 Atherothrombotic325 (24.2)19 (20.2)ns
 Cardioembolic565 (42.1)58 (61.7)0.025
 Lacunar60 (4.5)1 (1.1)ns
 Other determined aetiology72 (5.4)0ns
 Undetermined aetiology321 (23.9)16 (17)ns

NIHSS: National Institutes of Health Stroke Scale; IQR: interquartile range; BP: blood pressure. Statistical significance .