Research Article

Fibrinolytic Activity and Platelet Function in Subjects with Obstructive Sleep Apnoea and a Patent Foramen Ovale: Is There an Option for Prevention of Ischaemic Stroke?

Table 3

Urinary excretion of thromboxane and prostacyclin in subjects without PFO.

VariableControl OSA
DayNightDayNight

11 DH-TXB2, pg/μmol creatinine24 (8–41)18 (9–26)23 (19–28)24 (16–31)
2,3-dinor-TXB2, pg/μmol creatinine18 (11–26)15 (11–19)16 (12–19)15 (12–18)
2,3-dinor-PGF , pg/μmol creatinine15 (10–20)14 (9–19)11 (8–14)9 (6–12)*
2,3-dinor-TXB2/2,3-dinor-PGF 1.2 (0.9–1.5)1.2 (1.0–1.5)1.7 (1.0–2.3)1.8 (1.5–2.1)

* for difference between the subjects with OSA and the controls during night.