Poststroke Hip Fracture: Prevalence, Clinical Characteristics, Mineral-Bone Metabolism, Outcomes, and Gaps in Prevention

Table 3

Parameters of mineral and bone metabolism in older hip fracture patients with and without history of stroke.

Parameter	Poststroke HF	Without stroke HF	𝑃 value
Serum calcium*, mmol/L	2.27±0.12	2.28±0.13	0.730
Serum phosphate, mmol/L	0.89±0.30	0.96±0.50	0.428
Serum magnesium, mmol/L	0.77±0.12	0.78±0.13	0.887
25(OH)vitamin D, nmol/L	40.1±20.05	36.8±17.97	0.319
PTH, pmol/L	9.0±6.66	7.6±5.41	0.019
Osteocalcin, ng/L	13.8±8.44	18.0±16.18	0.025
BAP, IU/L	25.5±9.76	26.8±14.97	0.624
Osteocalcin/BAP ratio	0.59±0.37	0.78±0.78	0.026
Urinary DPD/Cr, nmol/𝜇mol	16.0±14.02	12.0±5.53	0.004
Urinary NTx/Cr, nmol/𝜇mol	207.9±279.0	149.7±141.3	0.056
BSI	−12.5±14.8	−8.6±6.1	0.009
PTH > 6.8 pmol/L, %	50.0	34.2	0.046
25(OH)D < 50 nmoL/L, %	68.0	81.7	0.044
25(OH) vitamin D < 25 nmol/L, %	27.0	31.0	0.626
Osteocalcin < 14.0 ng/L, %	57.0	51.9	0.582
BAP < 14.0 IU/L, %	11.0	9.3	0.734
Urinary DPD/Cr > 7.5 nmol/𝜇mol,%	90.0	81.9	0.189
Urinary NTx/Cr > 65 nmol/𝜇mol, %	78.0	71.6	0.444

The values are expressed as mean ± standard deviation (SD) or percentage.
*Adjusted for serum albumin. PTH: parathyroid hormone; BAP: bone specific alkaline phosphate; DPD/Cr: deoxypyridinoline corrected for urinary creatinine concentration; NTx/Cr: cross-linked N-telopeptide of type 1 collagen corrected for urinary creatinine concentration; BSI: bone balance status index.