Research Article

Targeting Oxidative Stress Injury after Ischemic Stroke in Conscious Rats: Limited Benefits with Apocynin Highlight the Need to Incorporate Long Term Recovery

Figure 6

Immunohistochemical localization of cortical NADPH oxidase subunit Nox2 in the stroke-affected cortex (b), (d) and the contralateral mirror image ((a), (c)), in vehicle control ((a), (b)) and apocynin- ((c), (d)) treated rats. Micrographs taken from the core infarct region 3 days after stroke show a reduction in Nox2 positive cells following apocynin treatment (d) compared with vehicle control (b). Scale bar = 50 μm.
648061.fig.006a
(a)
648061.fig.006b
(b)
648061.fig.006c
(c)
648061.fig.006d
(d)