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Stroke Research and Treatment
Volume 2013 (2013), Article ID 862978, 11 pages
http://dx.doi.org/10.1155/2013/862978
Review Article

Depression after Stroke and Risk of Mortality: A Systematic Review and Meta-Analysis

1Department of Surgery and Interdisciplinary Medicine, University of Milano-Bicocca, 20900 Monza, Italy
2Stroke Unit, Neurology Department, Azienda Ospedaliera Niguarda Cà Granda, 20162 Milan, Italy
3Department of Mental Health, Azienda Ospedaliera San Gerardo, 20900 Monza, Italy
4Department of Mental Health Sciences, University College London, London W1W 7EJ, UK

Received 12 October 2012; Revised 21 December 2012; Accepted 25 January 2013

Academic Editor: Caroline L. Watkins

Copyright © 2013 Francesco Bartoli et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. J. Mackay and G. A. Mensah, Deaths from Stroke. The Atlas of Heart Disease and Stroke, World Health Organization, Geneva, Switzerland, 2004, http://www.who.int/cardiovascular_diseases/en/cvd_atlas_16_death_from_stroke.pdf.
  2. J. A. Bourgeois, D. M. Hilty, C. H. Chang, M. A. Wineinger, and M. E. Servis, “Poststroke neuropsychiatric illness: an integrated approach to diagnosis and management,” Current Treatment Options in Neurology, vol. 6, no. 5, pp. 403–420, 2004. View at Scopus
  3. S. M. Lai, S. Studenski, P. W. Duncan, and S. Perera, “Persisting consequences of stroke measured by the stroke impact scale,” Stroke, vol. 33, no. 7, pp. 1840–1844, 2002. View at Publisher · View at Google Scholar · View at Scopus
  4. A. J. Carson, “Impact commentaries. Mood disorder as a specific complication of stroke,” Journal of Neurology, Neurosurgery & Psychiatry, vol. 83, no. 9, p. 859, 2012. View at Publisher · View at Google Scholar
  5. M. F. Folstein, R. Maiberger, and P. R. McHugh, “Mood disorder as a specific complication of stroke,” Journal of Neurology Neurosurgery and Psychiatry, vol. 40, no. 10, pp. 1018–1020, 1977. View at Scopus
  6. R. G. Robinson, W. J. Shoemaker, M. Schlumpf, T. Valk, and F. E. Bloom, “Effect of experimental cerebral infarction in rat brain on catecholamines and behaviour,” Nature, vol. 255, no. 5506, pp. 332–334, 1975. View at Scopus
  7. R. G. Robinson, “Poststroke depression: prevalence, diagnosis, treatment, and disease progression,” Biological Psychiatry, vol. 54, no. 3, pp. 376–387, 2003. View at Publisher · View at Google Scholar · View at Scopus
  8. O. P. Almeida and J. Xiao, “Mortality associated with incident mental health disorder after stroke,” Australian and New Zealand Journal of Psychiatry, vol. 41, no. 3, pp. 274–281, 2007. View at Publisher · View at Google Scholar · View at Scopus
  9. C. Ellis, Y. Zhao, and L. E. Egede, “Depression and increased risk of death in adults with stroke,” Journal of Psychosomatic Research, vol. 68, no. 6, pp. 545–551, 2010. View at Publisher · View at Google Scholar · View at Scopus
  10. A. House, P. Knapp, J. Bamford, and A. Vail, “Mortality at 12 and 24 months after stroke may be associated with depressive symptoms at 1 month,” Stroke, vol. 32, no. 3, pp. 696–701, 2001. View at Scopus
  11. H. Jia, T. M. Damush, H. Qin et al., “The impact of poststroke depression on healthcare use by veterans with acute stroke,” Stroke, vol. 37, no. 11, pp. 2796–2801, 2006. View at Publisher · View at Google Scholar · View at Scopus
  12. R. E. Jorge, R. G. Robinson, S. Arndt, and S. Starkstein, “Mortality and poststroke depression: a placebo-controlled trial of antidepressants,” American Journal of Psychiatry, vol. 160, no. 10, pp. 1823–1829, 2003. View at Publisher · View at Google Scholar · View at Scopus
  13. C. Kemper, D. Koller, G. Glaeske, and H. van den Bussche, “Mortality and nursing care dependency one year after first ischemic stroke: an analysis of German statutory health insurance data,” Topics in Stroke Rehabilitation, vol. 18, no. 2, pp. 172–178, 2011. View at Publisher · View at Google Scholar · View at Scopus
  14. P. L. P. Morris, R. G. Robinson, P. Andrzejewski, J. Samuels, and T. R. Price, “Association of depression with 10-year poststroke mortality,” American Journal of Psychiatry, vol. 150, no. 1, pp. 124–129, 1993. View at Scopus
  15. P. L. P. Morris, R. G. Robinson, and J. Samuels, “Depression, introversion and mortality following stroke,” Australian and New Zealand Journal of Psychiatry, vol. 27, no. 3, pp. 443–449, 1993. View at Scopus
  16. H. Naess, L. Lunde, J. Brogger, and U. Waje-Andreassen, “Depression predicts unfavourable functional outcome and higher mortality in stroke patients: the Bergen Stroke Study,” Acta Neurologica Scandinavica, vol. 122, no. 190, pp. 34–38, 2010. View at Publisher · View at Google Scholar · View at Scopus
  17. S. Paolucci, C. Gandolfo, L. Provinciali, R. Torta, V. Toso, and DESTRO Study Group, “The Italian multicenter observational study on post-stroke depression (DESTRO),” Journal of Neurology, vol. 253, no. 5, pp. 556–562, 2006. View at Publisher · View at Google Scholar · View at Scopus
  18. L. D. Ried, H. Jia, H. Feng et al., “Selective serotonin reuptake inhibitor treatment and depression are associated with poststroke mortality,” Annals of Pharmacotherapy, vol. 45, no. 7-8, pp. 888–897, 2011. View at Publisher · View at Google Scholar · View at Scopus
  19. J. Z. Willey, N. Disla, Y. P. Moon et al., “Early depressed mood after stroke predicts long-term disability: the Northern Manhattan Stroke Study (NOMASS),” Stroke, vol. 41, no. 9, pp. 1896–1900, 2010. View at Publisher · View at Google Scholar · View at Scopus
  20. L. S. Williams, S. S. Ghose, and R. W. Swindle, “Depression and other mental health diagnoses increase mortality risk after ischemic stroke,” American Journal of Psychiatry, vol. 161, no. 6, pp. 1090–1095, 2004. View at Publisher · View at Google Scholar · View at Scopus
  21. W. A. Gordon and M. R. Hibbard, “Poststroke depression: an examination of the literature,” Archives of Physical Medicine and Rehabilitation, vol. 78, no. 6, pp. 658–663, 1997. View at Publisher · View at Google Scholar · View at Scopus
  22. K. A. Spencer, C. A. Tompkins, and R. Schulz, “Assessment of depression in patients with brain pathology: the case of stroke,” Psychological Bulletin, vol. 122, no. 2, pp. 132–152, 1997. View at Scopus
  23. M. L. Hackett, C. Yapa, V. Parag, and C. S. Anderson, “Frequency of depression after stroke: a systematic review of observational studies,” Stroke, vol. 36, no. 6, pp. 1330–1340, 2005. View at Publisher · View at Google Scholar · View at Scopus
  24. L. de Wit, K. Putman, I. Baert et al., “Anxiety and depression in the first six months after stroke. A longitudinal multicentre study,” Disability and Rehabilitation, vol. 30, no. 24, pp. 1858–1866, 2008. View at Publisher · View at Google Scholar · View at Scopus
  25. A. Srivastava, A. B. Taly, A. Gupta, and T. Murali, “Post-stroke depression: prevalence and relationship with disability in chronic stroke survivors,” Annals of Indian Academy of Neurology, vol. 13, no. 2, pp. 123–127, 2010. View at Publisher · View at Google Scholar · View at Scopus
  26. J. P. Fedoroff, S. E. Starkstein, R. M. Parikh, T. R. Price, and R. G. Robinson, “Are depressive symptoms nonspecific in patients with acute stroke?” American Journal of Psychiatry, vol. 148, no. 9, pp. 1172–1176, 1991. View at Scopus
  27. D. S. P. Schubert, R. Burns, W. Paras, and E. Sioson, “Increase of medical hospital length of stay by depression in stroke and amputation patients: a pilot study,” Psychotherapy and Psychosomatics, vol. 57, no. 1-2, pp. 61–66, 1992. View at Scopus
  28. K. Salter, S. K. Bhogal, N. Foley, J. Jutai, and R. Teasell, “The assessment of poststroke depression,” Topics in Stroke Rehabilitation, vol. 14, no. 3, pp. 1–24, 2007. View at Publisher · View at Google Scholar · View at Scopus
  29. T. Pohjasvaara, R. Vataja, A. Leppävuori, M. Kaste, and T. Erkinjuntti, “Depression is an independent predictor of poor long-term functional outcome post-stroke,” European Journal of Neurology, vol. 8, no. 4, pp. 315–319, 2001. View at Publisher · View at Google Scholar · View at Scopus
  30. R. Gillen, T. L. Eberhardt, H. Tennen, G. Affleck, and Y. Groszmann, “Screening for depression in stroke: relationship to rehabilitation efficiency,” Journal of Stroke and Cerebrovascular Diseases, vol. 8, no. 5, pp. 300–306, 1999. View at Publisher · View at Google Scholar · View at Scopus
  31. E. Chemerinski, R. G. Robinson, and J. T. Kosier, “Improved recovery in activities of daily living associated with remission of poststroke depression,” Stroke, vol. 32, no. 1, pp. 113–117, 2001. View at Scopus
  32. R. G. Robinson, K. Bolla-Wilson, E. Kaplan, J. R. Lipsey, and T. R. Price, “Depression influences intellectual impairment in stroke patients,” British Journal of Psychiatry, vol. 148, pp. 541–547, 1986. View at Scopus
  33. S. Serrano, J. Domingo, E. Rodríguez-Garcia, M. D. Castro, and T. del Ser, “Frequency of cognitive impairment without dementia in patients with stroke: a two-year follow-up study,” Stroke, vol. 38, no. 1, pp. 105–110, 2007. View at Publisher · View at Google Scholar · View at Scopus
  34. H. W. Yuan, C. X. Wang, N. Zhang et al., “Poststroke depression and risk of recurrent stroke at 1 year in a chinese cohort study,” PLoS One, vol. 7, article e46906, no. 10, 2012.
  35. P. L. P. Morris, R. G. Robinson, and B. Raphael, “Prevalence and course of depressive disorders in hospitalized stroke patients,” International Journal of Psychiatry in Medicine, vol. 20, no. 4, pp. 349–364, 1990. View at Scopus
  36. R. G. Robinson and G. Spalletta, “Poststroke depression: a review,” Canadian Journal of Psychiatry, vol. 55, no. 6, pp. 341–349, 2010. View at Scopus
  37. D. F. Stroup, J. A. Berlin, S. C. Morton et al., “Meta-analysis of observational studies in epidemiology: a proposal for reporting,” Journal of the American Medical Association, vol. 283, no. 15, pp. 2008–2012, 2000. View at Scopus
  38. Review Manager (RevMan), Version 5.1., The Nordic Cochrane Centre, The Cochrane Collaboration, Copenhagen, Denmark, 2011.
  39. StataCorp, Stata Statistical Software: Release 10, StataCorp LP, College Station, Tex, USA, 2007.
  40. S. Paolucci, “Epidemiology and treatment of post-stroke depression,” Neuropsychiatric Disease and Treatment, vol. 4, no. 1, pp. 145–154, 2008. View at Scopus
  41. M. Egger, M. Schneider, and G. D. Smith, “Meta-analysis spurious precision? meta-analysis of observational studies,” British Medical Journal, vol. 316, no. 7125, pp. 140–144, 1998. View at Scopus
  42. D. A. Grimes and K. F. Schulz, “Bias and causal associations in observational research,” The Lancet, vol. 359, no. 9302, pp. 248–252, 2002. View at Publisher · View at Google Scholar · View at Scopus
  43. A. Dossa, M. E. Glickman, and D. Berlowitz, “Association between mental health conditions and rehospitalization, mortality, and functional outcomes in patients with stroke following inpatient rehabilitation,” BMC Health Services Research, vol. 11, p. 311, 2011. View at Publisher · View at Google Scholar
  44. G. Carrà, S. Johnson, P. Bebbington et al., “The lifetime and past-year prevalence of dual diagnosis in people with schizophrenia across Europe: findings from the European Schizophrenia Cohort (EuroSC),” European Archives of Psychiatry and Clinical Neuroscience, vol. 262, no. 7, pp. 607–616, 2012. View at Publisher · View at Google Scholar
  45. M. L. Hackett and C. S. Anderson, “Predictors of depression after stroke: a systematic review of observational studies,” Stroke, vol. 36, no. 10, pp. 2296–2301, 2005. View at Publisher · View at Google Scholar · View at Scopus
  46. J. Blume, S. D. Douglas, and D. L. Evans, “Immune suppression and immune activation in depression,” Brain, Behavior, and Immunity, vol. 25, no. 2, pp. 221–229, 2011. View at Publisher · View at Google Scholar · View at Scopus
  47. J. Barth, M. Schumacher, and C. Herrmann-Lingen, “Depression as a risk factor for mortality in patients with coronary heart disease: a meta-analysis,” Psychosomatic Medicine, vol. 66, no. 6, pp. 802–813, 2004. View at Publisher · View at Google Scholar · View at Scopus
  48. G. Carrà, P. Sciarini, G. Segagni-Lusignani, M. Clerici, C. Montomoli, and R. C. Kessler, “Do they actually work across borders? Evaluation of two measures of psychological distress as screening instruments in a non Anglo-Saxon country,” European Psychiatry, vol. 26, no. 2, pp. 122–127, 2011. View at Publisher · View at Google Scholar · View at Scopus
  49. K. Mikami, R. E. Jorge, H. P. Adams Jr. et al., “Effect of antidepressants on the course of disability following stroke,” American Journal of Geriatric Psychiatry, vol. 19, no. 12, pp. 1007–1015, 2011. View at Publisher · View at Google Scholar
  50. L. Wiart, H. Petit, P. A. Joseph, J. M. Mazaux, and M. Barat, “Fluoxetine in early poststroke depression: a double-blind placebo-controlled study,” Stroke, vol. 31, no. 8, pp. 1829–1832, 2000. View at Scopus
  51. G. Andersen, K. Vestergaard, and L. Lauritzen, “Effective treatment of poststroke depression with the selective serotonin reuptake inhibitor citalopram,” Stroke, vol. 25, no. 6, pp. 1099–1104, 1994. View at Scopus
  52. L. Rampello, S. Chiechio, G. Nicoletti et al., “Prediction of the response to citalopram and reboxetine in post-stroke depressed patients,” Psychopharmacology, vol. 173, no. 1-2, pp. 73–78, 2004. View at Publisher · View at Google Scholar · View at Scopus
  53. L. Rampello, A. Alvano, S. Chiechio, R. Raffaele, I. Vecchio, and M. Malaguarnera, “An evaluation of efficacy and safety of reboxetine in elderly patients affected by "retarded" post-stroke depression: a random, placebo-controlled study,” Archives of Gerontology and Geriatrics, vol. 40, no. 3, pp. 275–285, 2005. View at Publisher · View at Google Scholar · View at Scopus
  54. M. L. Hackett, C. S. Anderson, A. House, and J. Xia, “Interventions for treating depression after stroke,” Cochrane Database of Systematic Reviews, no. 4, Article ID CD003437, 2008. View at Scopus
  55. M. L. Hackett, C. S. Anderson, A. House, and C. Halteh, “Interventions for preventing depression after stroke,” Cochrane Database of Systematic Reviews, no. 3, Article ID CD003689, 2008. View at Scopus
  56. G. Carrá, G. S. Lusignani, P. Sciarini, F. Barale, A. Marinoni, and M. Clerici, “And how shall we deal with adaptation and implementation of NICE schizophrenia guidelines in Italy?” Epidemiologia e Psichiatria Sociale, vol. 17, no. 4, pp. 258–262, 2008. View at Scopus