Research Article

Role of Matrix Metalloproteinase Activity in the Neurovascular Protective Effects of Angiotensin Antagonism

Figure 2

Effects of candesartan alone and in combination with FeTPPS and GM6001 on MMP activity at 24 h after MCAO. MMP-9 was significantly inhibited by FeTTPS alone and in combination with candesartan. Candesartan alone significantly increased MMP-9 when administered with DMSO, but GM6001 significantly reduced MMP activity. Values are mean ± SEM ( , ).
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