Role of Matrix Metalloproteinase Activity in the Neurovascular Protective Effects of Angiotensin Antagonism

<table>Schematic of experimental hypothesis for the possible mechanisms of candesartan-induced acute protection. ROS: reactive oxygen species, RNS: reactive nitrogen species, MMP: matrix metalloproteinases, FeTPPs: a peroxynitrite decomposition catalyst, 5,10,15,20-tetrakis (4-sulfonatophenyl)porphyrin to iron III chloride, and GM6001: a broad spectrum MMP Inhibitor.</table>

Stroke Research and Treatment

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Figure 5

Figure 5: Role of Matrix Metalloproteinase Activity in the Neurovascular Protective Effects of Angiotensin Antagonism 