The R18 Polyarginine Peptide Is More Effective Than the TAT-NR2B9c (NA-1) Peptide When Administered 60 Minutes after Permanent Middle Cerebral Artery Occlusion in the Rat

Figure 1

Infarct volume measurements 24 hours after permanent MCAO. Treatments were administered intravenously (saline vehicle or R18 and TAT-NR2B9c peptide at 100, 300, or 1000 nmol/kg; 600 μL volume over 6 min) 60 minutes after MCAO. Values are mean ± SD. when compared to the vehicle control group and when compared to the TAT-NR2B9c 100 nmol/kg group. † denotes animals that died several hours before the 24-hour post-MCAO study end-point but were still included in the final infarct volume analysis.