Variability in the Responsiveness to Low-Dose Aspirin: Pharmacological and Disease-Related Mechanisms

Table 3

Age-related plasma esterase activities.

Type of esterase	18–29 yrs	30–44 yrs	45–69 yrs	60–75 yrs	>75 yrs	>75 “fraile”
Ach esterase	2.78±0.4	3.35±0.1	3.1±0.2	3.3±0.2	3.13±0.3	1.96^∗±0.6
Aspirin esterase	162±27	161±18	146±11	147±10	128±22	64^∗±23

Correlation age-esterase activities: Ach 𝑟=−0.011, 𝑃=0.9; ASA 𝑟=−0.25, 𝑃=0.11; Ach: acetylcholine; yrs: years; *𝑃<0.005 versus nonfraile, old people. Data from [27, 28].