Copyright © 2012 Raghid Kreidy. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

1. A. N. Nicolaides, H. K. Breddin, P. Carpentier et al., “Thrombophilia and venous thromboembolism. International consensus statement. Guidelines according to scientific evidence,” International Angiology, vol. 24, no. 1, pp. 1–26, 2005. View at Scopus
2. M. Montagnana, E. J. Favaloro, M. Franchini, G. C. Guidi, and G. Lippi, “The role of ethnicity, age and gender in venous thromboembolism,” Journal of Thrombosis and Thrombolysis, vol. 29, no. 4, pp. 489–496, 2010. View at Publisher · View at Google Scholar · View at Scopus
3. L. N. Roberts, R. K. Patel, and R. Arya, “Venous thromboembolism and ethnicity,” British Journal of Haematology, vol. 146, no. 4, pp. 369–383, 2009. View at Publisher · View at Google Scholar · View at Scopus
4. W. H. Geerts, J. A. Heit, G. P. Clagett et al., “Prevention of venous thromboembolism,” Chest, vol. 119, no. 1, pp. S132–S175, 2001. View at Scopus
5. D. C. Rees, M. Cox, and J. B. Clegg, “World distribution of factor V Leiden,” Lancet, vol. 346, no. 8983, pp. 1133–1134, 1995. View at Scopus
6. N. Irani-Hakime, H. Tamim, R. Kreidy, and W. Y. Almawi, “Prevalence of factor V R506 Q-Leiden among apparently healthy Lebanese patients,” American Journal of Hematology, vol. 65, no. 1, pp. 45–49, 2000.
7. S. Moll, “Thrombophilias—practical implications and testing caveats,” Journal of Thrombosis and Thrombolysis, vol. 21, no. 1, pp. 7–15, 2006. View at Publisher · View at Google Scholar · View at Scopus
8. M. A. Crowther and J. G. Kelton, “Congenital thrombophilic states associated with venous thrombosis: a qualitative overview and proposed classification system,” Annals of Internal Medicine, vol. 138, no. 2, pp. 128–134, 2003. View at Scopus
9. G. A. F. Nicolaes and B. Dahlback, “Activated protein C resistance ( FVL ) and thrombosis: factor V mutations causing hypercoagulable states,” Hematology/Oncology Clinics of North America, vol. 17, no. 11, pp. 37–61, 2003.
10. L. H. Lee, T. C. Liu, P. Kuperan, L. K. Tan, D. Tan, and M. L. Poon, “Hereditary thrombophilia in an unselected cohort of venous thrombosis patients in Singapore,” Journal of Clinical Pathology, vol. 64, no. 9, pp. 814–817, 2011.
11. V. Roldan, R. Lecumberri, J. F. S. Muñoz-Torrero et al., “Thrombophilia testing in patients with venous thromboembolism. Findings from the RIETE registry,” Thrombosis Research, vol. 124, no. 2, pp. 174–177, 2009. View at Publisher · View at Google Scholar · View at Scopus
12. J. A. Friedline, E. Ahmad, D. Garcia et al., “Combined factor V Leiden and prothrombin genotyping in patients presenting with thromboembolic episodes,” Archives of Pathology and Laboratory Medicine, vol. 125, no. 1, pp. 105–111, 2001. View at Scopus
13. O. Wu, L. Robertson, S. Twaddle et al., “Screening for thrombophilia in high-risk situations: systematic review and cost-effectiveness analysis. The Thrombosis: Risk and Economic Assessment of Thrombophilia Screening (TREATS) study,” Health Technology Assessment, vol. 10, no. 11, pp. 1–75, 2006. View at Scopus
14. A. Hatzaki, E. Anagnostopoulou, V. Metaxa-Mariatou et al., “The impact of heterozygosity for the factor V Leiden and factor II G20210A mutations on the risk of thrombosis in Greek patients,” International Angiology, vol. 22, no. 1, pp. 79–82, 2003. View at Scopus
15. A. Ajem, A. Slama, F. B. H. Slama, and T. Mehjoub, “Prevalence of factor V Leiden mutation in patients with thrombosis in Tunisia,” Eastern Mediterranean Health Journal, vol. 15, no. 6, pp. 1483–1488, 2009. View at Scopus
16. B. S. Andersen and J. Olsen, “Oral contraception and factor V Leiden mutation in relation to localization of deep vein thrombosis,” Thrombosis Research, vol. 90, no. 4, pp. 191–194, 1998. View at Publisher · View at Google Scholar · View at Scopus
17. P. Dulíček, J. Malý, L. Pešavová, and M. Pecka, “Prevalence of inherited thrombophilia in young thrombosis patients from the East Bohemian region,” Blood Coagulation and Fibrinolysis, vol. 13, no. 6, pp. 569–573, 2002. View at Publisher · View at Google Scholar · View at Scopus
18. K. Ghosh, S. Shetty, M. Madkaikar et al., “Venous thromboembolism in young patients from Western India: a study,” Clinical and Applied Thrombosis/Hemostasis, vol. 7, no. 2, pp. 158–165, 2001. View at Scopus
19. S. Unal, G. Balta, F. Duru, F. Gumruk, C. Altay, and A. Gurgey, “Clinical and laboratory evaluation of Turkish children with thrombosis for homozygous factor V G1691A mutation,” Blood Coagulation and Fibrinolysis, vol. 15, no. 4, pp. 343–346, 2004. View at Publisher · View at Google Scholar · View at Scopus
20. I. Aschka, V. Aumann, F. Bergmann et al., “Prevalence of factor V leiden in children with thrombo-embolism,” European Journal of Pediatrics, vol. 155, no. 12, pp. 1009–1014, 1996. View at Publisher · View at Google Scholar · View at Scopus
21. A. Marchiori, L. Mosena, M. H. Prins, and P. Prandoni, “The risk of recurrent venous thromboembolism among heterozygous carriers of factor V Leiden or prothrombin G20210A mutation. A systematic review of prospective studies,” Haematologica, vol. 92, no. 8, pp. 1107–1114, 2007. View at Publisher · View at Google Scholar · View at Scopus
22. U. Nowak-Göttl, R. Junker, W. Kreuz et al., “Risk of recurrent venous thrombosis in children with combined prothrombotic risk factors,” Blood, vol. 97, no. 4, pp. 858–862, 2001. View at Publisher · View at Google Scholar · View at Scopus
23. E. R. Pomp, A. M. Lenselink, F. R. Rosendaal, and C. J. M. Doggen, “Pregnancy, the postpartum period and prothrombotic defects: risk of venous thrombosis in the MEGA study,” Journal of Thrombosis and Haemostasis, vol. 6, no. 4, pp. 632–637, 2008. View at Publisher · View at Google Scholar · View at Scopus
24. C. Legnani, B. Cosmi, L. Valdrè et al., “Venous thromboembolism, oral contraceptives and high prothrombin levels,” J Thromb Haemost, vol. 1, no. 1, pp. 112–117, 2003. View at Scopus
25. J. P. Vandenbroucke, T. Koster, E. Briet, P. H. Reitsma, R. M. Bertina, and F. R. Rosendaal, “Increased risk of venous thrombosis in oral-contraceptive users who are carriers of factor V Leiden mutation,” Lancet, vol. 344, no. 8935, pp. 1453–1457, 1994. View at Publisher · View at Google Scholar · View at Scopus
26. M. Procházka, V. Krcová, P. Hrachovec, M. Kudela, and L. Slavík, “Activated protein C resistance and deep venous thrombosis in pregnancy,” Ceska Gynekologie, vol. 67, no. 5, pp. 251–254, 2002. View at Scopus
27. J. Paseka, V. Unzeitig, D. Cibula, A. Bulikova, M. Matykova, and K. Chroust, “Factor V Leiden in oral contraceptives users,” Ceska Gynekologie, vol. 65, no. 3, pp. 156–159, 2000. View at Scopus
28. J. W. Blom, C. J. M. Doggen, S. Osanto, and F. R. Rosendaal, “Malignancies, prothrombotic mutations, and the risk of venous thrombosis,” Journal of the American Medical Association, vol. 293, no. 6, pp. 715–722, 2005. View at Publisher · View at Google Scholar · View at Scopus
29. P. Prandoni, “Cancer and thromboembolic disease: how important is the risk of thrombosis?” Cancer Treatment Reviews, vol. 28, no. 3, pp. 133–136, 2002. View at Publisher · View at Google Scholar · View at Scopus
30. M. Mandalà, S. Barni, M. Prins et al., “Acquired and inherited risk factors for developing venous thromboembolism in cancer patients receiving adjuvant chemotherapy: a prospective trial,” Advances in Gastrointestinal Cancers, vol. 21, no. 4, pp. 871–879, 2009. View at Publisher · View at Google Scholar · View at Scopus
31. W. H. Geerts, G. F. Pineo, J. A. Heit et al., “Prevention of venous thromboembolism: the 7th ACCP conference on antithrombotic and thrombolytic therapy,” Chest, vol. 126, no. 3, supplement, pp. 338S–400S, 2004. View at Publisher · View at Google Scholar · View at Scopus
32. W. Schobersberger, B. Schobersberger, and H. Partsch, “Travel-related thromboembolism: mechanisms and avoidance,” Expert Review of Cardiovascular Therapy, vol. 7, no. 12, pp. 1559–1567, 2009. View at Publisher · View at Google Scholar · View at Scopus
33. J. Siedenburg, “Traveler’s thrombosis. Who is at risk-low to prevent it,” Münchener Medizinische Wochenschrift, vol. 144, no. 38, pp. 39–41, 2002.
34. S. R. Poort, F. R. Rosendaal, P. H. Reitsma, and R. M. Bertina, “A common genetic variation in the 3'-untranslated region of the prothrombin gene is associated with elevated plasma prothrombin levels and an increase in venous thrombosis,” Blood, vol. 88, no. 10, pp. 3698–3703, 1996. View at Scopus
35. V. De Stefano, P. Chiusolo, K. Paciaroni, and G. Leone, “Epidemiology of factor V Leiden: clinical implications,” Seminars in Thrombosis and Hemostasis, vol. 24, no. 4, pp. 367–379, 1998. View at Scopus
36. G. Palareti, “Current criteria to determine the duration of anticoagulant therapy,” Recenti Progressi in Medicina, vol. 98, no. 12, pp. 603–606, 2007. View at Scopus