Figure 1: Major and minor vascular events through the course of the disease. The timing of vascular complication was known for 13 men and 41 women. In both men and women, vascular complications often lead to an official diagnosis of a myeloproliferative neoplasm (complication at year 0). Further, vascular complications predominantly occurred in the first decade of disease in both men and women. Of the 15 women with vascular complications at year 0, 9 had abdominal venous thrombosis.