Lack of Association between Recurrent Pregnancy Loss and Inherited Thrombophilia in a Group of Colombian Patients
Table 2
Genotype frequency of thrombophilias.
SNP
Genotype
Cases, (%)
Controls, (%)
OR (CI 95%)
FV Leiden
GG (normal)
92 (98.9%)
205 (99.5%)
0.4 (0–16.44)
GA
1 (1.1%)
1 (0.5%)
2.2 (0–83)
AA
0
0
ND
Total
93 (100%)
206 (100%)
FII G20210A
GG (normal)
92 (98.9%)
205 (99.5%)
0.4 (0–16.4)
GA
1 (1.1%)
1 (0.5%)
2.2 (0–83)
AA
0
0
ND
Total
93 (100%)
206 (100%)
MTHFR C677T
CC (normal)
38 (40.9%)
93 (45.1%)
0.8 (0.5–1.4)
CT
43 (46.2%)
83 (40%)
1.3 (0.8–2.1)
TT
12 (12.9%)
30 (14.9%)
0.8 (0.4–1.8)
Total
93 (100%)
206 (100%)
SNP: single nucleotide polymorphism; : number of women; OR: odds ratio; CI 95%: Cornfield’s 95% confidence interval for the OR; ND: not determined (0% frequency); FV: factor V; FII: prothrombin; MTHFR: methylenetetrahydrofolate reductase.
