Reversible Crystallization of Argatroban after Subcutaneous Application in Pigs

Figure 1

Plasma concentrations in pigs after s.c. administration of 0.5 mg·kg⁻¹ of argatroban in two different formulations: sorbitol/ethanol (open circles) and saline solution (closed circles). Results are expressed as the mean plasma concentration (μg·mL⁻¹) of 𝑛=5, showing the standard deviation at each sampling time.