Table 1: Genetic risks factor in venous thromboembolism (adapted from [38]).

Genetic riskDefficiency or alterationFrequency in patients with thrombosis

Strong genetic riskAntithrombin2–5%
Protein C2–5%
Protein S2–5%
Moderate genetic riskFactor V Leiden1835%
Prothrombin G20210A7–10%
Homocystinemia18–20%
Dysfibrinogehemia10%
Variable genetic riskElevated levels FI. FVIII, FIX, FXI15–30%
Acquired conditionAntiphospholipid antibody/syndrome5–10%
Pregnancy
Cancer