Factor V Leiden and Inflammation

Table 1

Genetic risks factor in venous thromboembolism (adapted from [38]).

Genetic risk	Defficiency or alteration	Frequency in patients with thrombosis
Strong genetic risk	Antithrombin	2–5%
	Protein C	2–5%
	Protein S	2–5%
Moderate genetic risk	Factor V Leiden	18–35%
	Prothrombin G20210A	7–10%
	Homocystinemia	18–20%
	Dysfibrinogehemia	10%
Variable genetic risk	Elevated levels FI. FVIII, FIX, FXI	15–30%
Acquired condition	Antiphospholipid antibody/syndrome	5–10%
	Pregnancy	—
	Cancer	—