Review Article
Towards Personalized Medicine Based on Platelet Function Testing for Stent Thrombosis Patients
Table 2
Cut-off values to determine high on-treatment platelet reactivity.
| Platelet function test | Cut-off value | Reference |
| P2Y12 inhibitor |
| VerifyNow P2Y12 | >235 PRU | Breet et al., [7] | Light transmittance aggregometry | | | 5 mol/L ADP | >42.9% | Breet et al., [7] | 20 mol/L ADP | >64.5% | Breet et al., [7] | VASP assay | >50% | Bonello et al., [74] |
| Aspirin |
| VerifyNow aspirin | >454 ARU | Breet et al., [7] | Light transmittance aggregometry | | | 0.5 mg/mL arachidonic acid | >20.0% | Gum et al., [50] | PFA-100 Col/EPI | <193 seconds | Frelinger et al., [46] |
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ADP: adenosine diphosphate; ARU: aspirin reaction unit; Col/ADP: collagen/ADP; Col/EPI: collagen/epinephrine; PFA-100: platelet function analyzer-100; PRU: P2Y12 reaction units; VASP: vasodilator-stimulated phosphoprotein.
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