Table 2: Cut-off values to determine high on-treatment platelet reactivity.

Platelet function testCut-off valueReference

P2Y12 inhibitor

VerifyNow P2Y12>235 PRUBreet et al., [7]
Light transmittance aggregometry
 5  mol/L ADP>42.9%Breet et al., [7]
 20  mol/L ADP>64.5%Breet et al., [7]
VASP assay>50%Bonello et al., [74]

Aspirin

VerifyNow aspirin>454 ARUBreet et al., [7]
Light transmittance aggregometry
 0.5 mg/mL arachidonic acid>20.0%Gum et al., [50]
PFA-100 Col/EPI<193 secondsFrelinger et al., [46]

ADP: adenosine diphosphate; ARU: aspirin reaction unit; Col/ADP: collagen/ADP; Col/EPI: collagen/epinephrine; PFA-100: platelet function analyzer-100; PRU: P2Y12 reaction units; VASP: vasodilator-stimulated phosphoprotein.